Journal article

Voice in Friedreich Ataxia

AP Vogel, MI Wardrop, JE Folker, M Synofzik, LA Corben, MB Delatycki, SN Awan

Journal of Voice | MOSBY-ELSEVIER | Published : 2017

Abstract

Background Friedreich Ataxia (FRDA) is the most common hereditary ataxia, with dysarthria as one of its key clinical signs. Objective To describe the voice profile of individuals with FRDA to inform outcome marker development and goals of speech therapy. Methods Thirty-six individuals with FRDA and 30 age-matched controls provided sustained vowel and connected speech samples. Speech and voice samples were analyzed acoustically using the Analysis of Dysphonia in Speech and Voice program and perceptually using the Consensus Auditory-Perceptual Evaluation of Voice form. Correlations between dysphonia and overall dysarthria severity, demographic, clinical, and genetic information were explored. ..

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Grants

Awarded by National Health and Medical Research Council, Australia


Awarded by National Health and Medical Research Council of Australia


Funding Acknowledgements

Dr. SN Awan is a consultant to Pentax Medical/KayPENTAX (Montvale, NJ) for the development of commercial computer software including cepstral analysis of continuous speech algorithms. KayPENTAX licenses the algorithms that form the basis of the Analysis of Dysphonia in Speech & Voice (ADSV) program from Dr. Awan. APV is funded by the National Health and Medical Research Council, Australia (1082910) (Career Development Award) and the Alexander von Humboldt Foundation, Germany.